李学松 主任医师

北京大学第一医院    泌尿外科

收治疾病: 前列腺癌 膀胱癌
治疗特色: 手术治疗
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专家履历
擅长

泌尿系肿瘤的腔镜及开放手术,腹腔镜肾脏部分切除术。腹腔镜肾癌根治术+淋巴结清扫,经腹完全腹腔镜肾输尿管全长切除术,腹腔镜及开放保留神经前列腺癌根治术,膀胱肿瘤电切术,膀胱癌根治术+盆腔淋巴结清扫术+回肠原位新膀胱术,腹腔镜和开放手术治疗输尿管疾病(包括输尿管长段缺损的肠代输尿管术)。晚期肾癌靶向药物治疗。

个人简介

"北京大学第一医院泌尿外科主任医师,1999年毕业于北京医科大学临床医学系,获学士学位。同年免试保送研究生,师从北京大学泌尿外科研究所薛兆英教授和郭应禄院士。2004年获北京大学医学部泌尿外科临床医学博士学位,并被评为北京大学优秀毕业生。同年任主治医师,2009晋升为副主任医师,2012年晋升为副教授,2016年晋升为主任医师。2009年-2010年美国旧金山大学医学院(UCSF) 访问学者、2013年3月-5月,美国南加州大学医学院(USC)访问学者。现为中国医师协会泌尿外科医师分会第二届委员兼副总干事,中华医学会泌尿外科学分会青年委员、,北京医学会泌尿外科学分会青年委员会副主任委员、中国医促会泌尿生殖委员会第一届委员,WHO泌尿外科疾病国际共识(SIU-ICUD)咨询委员会成员,中国医师协会全国医师定期考核泌尿外科专业编委会工作秘书、北京市自然科学基金评审专家、强生泌尿外科腹腔镜高级培训班讲师、美国泌尿外科学会(AUA)国际会员、2014及2015年度中国医师百强榜膀胱癌专业上榜专家、2015年度第一届郭应禄泌尿外科青年医师奖获得者。目前担任《泌尿男科时讯》编辑部主任,《Current Opinion in Urology》中文版编辑部主任,《泌尿外科杂志(电子版)》副主编、《现代泌尿外科杂志》、《Translational Andrology and Urology》和《Journal of Tumor》编委,《中华临床医师杂志》和《北京大学学报医学版》特约编委,《Andrology》、《Annals of Surgical Oncology 》《Oncotarget 》、《Urology》、《Canadian Journal of urology》、《Clinical Genitourinary Cancer》、《Chinese medical Journal》及《Urology Annals》等英文杂志以及《中国医学科学院学报》等中文杂志审稿专家。目前专业方向为泌尿系肿瘤以及输尿管和膀胱重建手术。参与科研基金项目6项。其中作为主要申请人承担基础及临床研究基金4项,累计科研经费80余万元。目前作为导师及副导师指导临床研究生20余名,已指导毕业博士研究生5名。 在国内最早较大规模的报道完全经腹腹腔镜肾脏输尿管全长切除手术,并改进输尿管末端袖状切除技术;优化经腹腹腔镜肾癌根治手术的关键步骤;改进腹腔镜膀胱癌根治及回肠原位新膀胱技术;在北大医院泌尿科首次完成肠代输尿管治疗疑难的长段输尿管缺损病例,并进行关键技术改良,后续的二十几例肠代输尿管手术患者临床疗效超过国际报道的水平;改良并标准化经腹腹腔镜肾盂成型缝合技术,降低缝合技术难度,缩短手术时间,提高了手术成功率。与普通外科合作进行腹腔镜全盆腔脏器切除术治疗晚期和复发盆腔肿瘤,减少了手术创伤,缩短了患者术后恢复时间。有多项创新改良手术技术:如成人巨输尿管体外裁剪乳头成型体内再植、经腹腹腔镜肾盂成型手术、改良肠代输尿管手术、输尿管末端袖状切术、腹腔镜肾部分切除内部悬吊技术等手术方法,作为新型手术技术在国际上被认可,发表在《Urology》等国际知名杂志的手术技术栏目上。成人巨输尿管腹腔镜手术和腔内治疗的比较研究被2016年美国AUA年会选为大会发言,马蹄肾成型手术入选2017年AUA视频集锦。 自2009年起,每年在北京大学泌尿外科研究所主办的国际微创技术学习班中表演经腹腹腔镜肾癌根治术、肾输尿管全长切除术,腹腔镜肾盂成型等手术。2015年,受亚洲泌尿年会组委会邀请在亚洲泌尿年会上做腹腔镜肾盂成型手术演示。此外,在过去的7年中,接受全国数十家医学中心邀请,做手术演示、手术会诊及会议讲座。 在医学研究方面,开展了国内最早最大规模对小肾癌体内的自然病程研究,研究目前已经长达13年,发表数篇SCI文章及核心期刊论文,增进了医学界对小肾癌自然病程,手术方式选择,疾病进展及预后的了解,在2015年的国际泌尿年会(SIU)上作为肾肿瘤国际共识撰写专家参与ICUD肾脏肿瘤的撰写和大会汇报;在针对上尿路尿路上皮肿瘤(UTUC)的系列研究中发现了中国人群特有的疾病特征,目前UTUC相关系列研究结果在国际上引起广泛关注,并对临床诊治指南提供了中国的循证医学证据,其中上尿路肿瘤术后膀胱灌注的荟萃分析结果被欧洲(EAU)的UTUC指南引用。在国内最早并系列报道晚期肾癌靶向药物治疗效果及不良反应数据,提出中国患者与西方国家具有一定差异,为国内同道用药提供参考。参与多项国际多中心临床药物试验研究,在多吉美、索坦、阿西替尼等治疗晚期肾癌靶向药物的临床研究中积累了丰富的临床经验。在担任中国肾癌病人援助项目指定医生期间先后诊治全国各地的晚期肾癌患者上百例。"代表性文章 (#第一作者; *通讯作者) SCI文章 1. He A, He S, Huang C, ... Li X* et al. MTDH promotes metastasis of clear cell renal cell carcinoma by activating SND1-mediated ERK signaling and epithelial-mesenchymal transition. Aging (Albany NY). 2020;12(2):1465-1487. (IF 4.831) 2. Zhan Y, Chen Z, He S, ... Li X* et al. Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2. Mol Cancer. 2020;19(1):25. (IF 15.302) 3. Xiong S, Zhu W, Li X, Zhang P, Wang H, Li X*. Intestinal interposition for complex ureteral reconstruction: A comprehensive review. Int J Urol. 2020;27(5):377-386. (IF 2.445) 4. Lu H, Liang Y, Guan B, ... Li X* et al. Aristolochic acid mutational signature defines the low-risk subtype in upper tract urothelial carcinoma. Theranostics. 2020;10(10):4323-4333. (IF 8.579) 5. Wang J, Xiong S, Fan S, ... Li X * et al. Appendiceal Onlay Flap Ureteroplasty for the Treatment of Complex Ureteral Strictures: Initial Experience of Nine Patients. J Endourol. 2020;34(8):874-881. (IF 2.322) 6. Ji G, Huang C, He S, ... Li X* et al. Comprehensive analysis of m6A regulators prognostic value in prostate cancer. Aging (Albany NY). 2020;12(14):14863-14884. (IF 4.831) 7. Xiong S, Wang J, Zhu W, ... Li X * et al. Onlay Repair Technique for the Management of Ureteral Strictures: A Comprehensive Review. Biomed Res Int. 2020; 2020:6178286. (IF 2.276) 8. Fan S, Yin L, Yang K, ... Li X * et al. Posteriorly augmented anastomotic ureteroplasty with lingual mucosal onlay grafts for long proximal ureteral strictures: Ten cases of experience. J Endourol. 2020. (IF 2.322) 9. Cheng S, Fan S, Wang J, ... Li X* et al. Laparoscopic and robotic ureteroplasty using onlay flap or graft for the management of long proximal or middle ureteral strictures: our experience and strategy[J]. International Urology and Nephrology, 2020(7):1-10. (IF 1.843) 10. Bao Guan #, Shiying Tang #, Yonghao Zhan #, Yifan Li, Dong Fang, Ding Peng, Yanqing Gong, Shiming He, Lei Zhang, Kunlin Yang, Gengyan Xiong, Libo Liu, Qun He, Xuesong Li*, Liqun Zhou*. Prognostic performance of the 1973 and 2004 WHO grading classification in upper tract urothelial carcinoma. Urol Oncol. 2019. (IF 3.397) 11. Yifan Li #, Bao Guan #, Jingtao Liu #, Zhongyuan Zhang, Shiming He, Yonghao Zhan, Boxing Su, Haibo Han, Xiaochun Zhang, Boqing Wang, Xuesong Li*, Liqun Zhou*, Wei Zhao*. MicroRNA-200b is downregulated and suppresses metastasis by targeting LAMA4 in renal cell carcinoma. EBioMedicine. 2019. (IF 6.183) 12. Yifan Li#, Shiming He#, Anbang He, Bao Guan, Guangzhe Ge, Yonghao Zhan, Yucai Wu, Yanqing Gong, Ding Peng, Zhengqing Bao, Xuesong Li*, Liqun Zhou*. Identification of plasma secreted phosphoprotein 1 as a novel biomarker for upper tract urothelial carcinomas. Biomed Pharmacother. 2019; 113: 108744. (IF 3.457) 13. Wenlong Zhong#, Peng Hong#, Guangpu Ding#, Kunlin Yang, Xuesong Li*, Junsheng Bao, Guochang Bao,Liang Cui, Changping Men, Zhe Li, Peng Zhang, Ning Chu and Liqun Zhou*. Technical considerations and outcomes for ileal ureter replacement: a retrospective study in China. BMC Surgery, 2019; 19:9. (IF 1.692) 14. Peng Hong#, Ziao Li#, Dongdong Zhu#, Liyan Zhuang, Kunlin Yang, Han Hao, Xuesong Li*, Liqun Zhou*. A Simple Modification for the Usage of Flexible Cystoscope in Modified Laparoscopic Pyeloplasty for Ureteropelvic Junction Obstruction with Renal Calculi: A Flexible Guiding Tube. Urol Int. 2019;102(3):262-268. (IF 1.508) 15. Yifan Li#, Dong Fang#, Zhengqing Bao#, Anbang He, Bao Guan, Shiming He, Yonghao Zhan, Yanqing Gong, Xuesong Li*, Liqun Zhou*. High aspartate transaminase/alanine transaminase ratio predicts poor prognosis in patients with localized upper tract urothelial cancer: a propensity score-matched study in a large Chinese center. OncoTargets Ther, 2019;12:2635-2648. (IF 2.656) 16. Peng Hong, Yukun Cai, Ziao Li, Shubo Fan, Kunlin Yang, Han Hao, Qun He, Xuesong Li*, Liqun Zhou*. Modified Laparoscopic Partial Ureterectomy for Adult Ureteral Fibroepithelial Polyp: Technique and Initial Experience. Urol Int. 2018;102(1):13-19. (IF 1.508) 17. Zhuo Jia#, Yanqing Gong#, Cuijian Zhang, Zhengqing Bao, Xuesong Li*, Han Hao, Gengyan Xiong, Lei Zhang, Dong Fang, Zhisong He, Liqun Zhou*. Segmental ureterectomy can be performed safely in patients with urothelial carcinoma of distal ureter. Can Urol Assoc J. 2018;13(7). (IF 1.179) 18. Yifan Li#, Yanqing Gong#, Xianghui Ning, Ding Peng, Libo Liu, Shiming He, Kan Gong, Cuijian Zhang*, Xuesong Li* and Liqun Zhou*. Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis. J Exp Clin Cancer Res. 2018;37(1):276. (IF 6.217) 19. Yonghao Zhan, Zhicong Chen, Yifan Li, Anbang He, Shiming He, Yanqing Gong, Xuesong Li* and Liqun Zhou*. Long non-coding RNA DANCR promotes malignant phenotypes of bladder cancer cells by modulating the miR-149/MSI2 axis as a ceRNA. J Exp Clin Cancer Res. 2018;37(1):273. (IF 6.217) 20. Anbang He#, Shiming He#, Xuesong Li*, Liqun Zhou*. ZFAS1: A novel vital oncogenic lncRNA in multiple human cancers. Cell Proliferation. 2018;66(4): e12513. (IF 4.936) 21. Ding Peng, Guangzhe Ge, Zhengzheng Xu, Qin Ma, Yue Shi, Yuanyuan Zhou, Yanqing Gong, Gengyan Xiong, Cuijian Zhang, Shiming He, Zhisong He, Xuesong Li*, Weimin Ci* and Liqun Zhou*. Diagnostic and prognostic biomarkers of common urological cancers based on aberrant DNA methylation. Epigenomics. 2018;10(9):1189-1199. (IF 4.979) 22. Zhicong Chen#, Yonghao Zhan#, Jieshan Chi#, Shuyuan Guo#, Xinliang Zhong, Anbang He, Jianrong Zheng, Yanqing Gong, Xuesong Li*, Liqun Zhou*. Using microRNAs as Novel Predictors of Urologic Cancer Survival: An Integrated Analysis. EBioMedicine. 2018; 34:94-107. (IF 6.183) 23. Guangzhe Ge#, Ding Peng#, Ziying Xu#, Bao Guan, Zijuan Xin, Qun He, Yuanyuan Zhou, Xuesong Li*, Liqun Zhou* and Weimin Ci*. Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth. EMBO Reports. 2018;19(8): e45401. (IF 8.749) 24. Ding Peng, Guangzhe Ge, Yanqing Gong, Yonghao Zhan, Shiming He, Bao Guan, Yifan Li, Ziying Xu, Han Hao, Zhisong He Gengyan Xiong, Cuijian Zhang, Yue Shi, Yuanyuan Zhou, Weimin Ci*, Xuesong Li* and Liqun Zhou*. Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer. Clin Epigenetics. 2018;10(1):94. (IF 6.091) 25. Bao Guan#, Yunchao Xing#, Gengyan Xiong#, Zhenpeng Cao, Dong Fang, Yifan Li, Yonghao Zhan, Ding Peng, Libo Liu, Xuesong Li* and Liqun Zhou*. Predictive value of gene methylation for second recurrence following surgical treatment of first bladder recurrence of a primary upper-tract urothelial carcinoma. Oncology Letters. 2018;15(6):9397-9405. (IF 1.664) 26. Ding Peng#, Cuijian Zhang#, Yanqing Gong*, Han Hao, Bao Guan, Xuesong Li* and Liqun Zhou*. Prognostic significance of HALP (hemoglobin, albumin, lymphocyte and platelet) in patients with bladder cancer after radical cystectomy. Scientific Reports. 2018; 8:794. (IF 4.122) 27. Ding Peng#, Cui-jian Zhang#, Qi Tang, Lei Zhang, Kai-wei Yang, Xiao-teng Yu, Yanqing Gong, Xue-song Li*, Zhi-song He and Li-qun Zhou*. Prognostic significance of the combination of preoperative hemoglobin and albumin levels and lymphocyte and platelet counts (HALP) in patients with renal cell carcinoma after nephrectomy. BMC Urol, 2018, 18:20. (IF 1.792) 28. Dong Fang#, Shiming He#, Gengyan Xiong#, Nirmish Singla, Zhenpeng Cao, Lei Zhang, Xuesong Li* and Liqun Zhou*. Comparison of clinicopathologic characteristics, epigenetic biomarkers and prognosis between renal pelvic and ureteral tumors in upper tract urothelial carcinoma. BMC Urol. 2018;18(1):22. (IF 1.792) 29. Bao Guan#, Yicong Du#, Xiaohong Su#, Zhenpeng Cao, Yifan Li, Yonghao Zhan, Ding Peng, Gengyan Xiong, Dong Fang, Yi Ding, Shiming He, Yanqing Gong, Qun He, Xuesong Li* and Liqun Zhou*. Positive urinary fluorescence in situ hybridization indicates poor prognosis in patients with upper tract urothelial carcinoma. Oncotarget. 2018;9(18):14652-14660. 30. Run-Qi Guo#, Geng-Yan Xiong#, Kai-Wei Yang, Lei Zhang, Shi-Ming He, Yan-Qing Gong, , Qun He, Xue-Ying Li, Zi-Cheng Wang, Zhen-Qing Bao, Xue-Song Li*, Kai Zhang, Li-Qun Zhou*. Detection of urothelial carcinoma, upper tract urothelial carcinoma, bladder carcinoma, and urothelial carcinoma with gross hematuria using selected urine-DNA methylation biomarkers: A prospective, single-center study. Urol Oncol. 2018; 36(7): 342.e15-342.e23. (IF 3.397) 31. Shiying Tang, Han Hao, Dong Fang, Wei Zheng, Peng Ge, Xiaohong Su, Qun He, Xinyu Yang , Qi Shen, Xuesong Li*, Wei Yu, Jian Lin, Liqun Zhou. Prostate cancer incidentally discovered at the time of radical cystoprostatectomy does not decrease overall survival: Results from a large Chinese medical center. Int Braz J Urol. 2018;44(2):258-266. (IF 0.976) 32. Peng Hong, Guangpu Ding, Dongdong Zhu, Kunlin Yang, Jinhong Pan*, Xuesong Li*, Zhipeng Chen, Lei Zhang, Qi Tang, Han Hao, Zhansong Zhou and Liqun Zhou. Head-to-Head Comparison of Modified Laparoscopic Pyeloplasty and Robot-Assisted Pyeloplasty for Ureteropelvic Junction Obstruction in China. Urol Int. 2018; 101(3):337-344. (IF 1.508) 33. Gengyan Xiong#, Lin Yao#, Peng Hong#, Li Yang, Weimin Ci, Libo Liu, Qun He, Kan Gong, Xuesong Li* and Liqun Zhou*. Aristolochic acid containing herbs induce gender-related oncological differences in upper tract urothelial carcinoma patients. Cancer Manag Res. 2018;10: 6627-6639. (IF 3.702) 34. Wenlong Zhong#, Lin Yao#, Haoran Cui, Kunlin Yang, Gang Wang, Tao Xu, Xiongjun Ye, Xuesong Li*, Liqun Zhou*. Laparoscopic ureteral reimplantation with extracorporeal tailoring and direct nipple ureteroneocystostomy for adult obstructive megaureter: long-term outcomes and comparison to open procedure. Int Urol Nephrol. 2017;49(11):1973-1978. (IF 1.692) 35. Shiying Tang#, Guochen Niu#, Dong Fang, Ziguang Yan, Bihui Zhang, Xuesong Li*, Min Yang*, Liqun Zhou*. The diagnosis and endovascular therapy of renal artery aneurysm: A 32-patient case report. Medicine (Baltimore). 2017;96(47): e8615. (IF 2.028) 36. Wenlong Zhong#, Yicong Du#, Kunlin Yang, Steven Meng, Rongcheng Lin, Xuesong Li*, Liyan Zhuang, Lin Cai, Haoran Cui, Zhisong He, and Liqun Zhou. Ileal Ureter Replacement Combined with Boari Flap-Psoas Hitch to Treat Full-Length Ureteral Defects: Technique and Initial Experience. Urology. 2017;108: 201-206. (IF 2.3) 37. ZhenPeng Cao, Bao Guan, GuangZhi Zhao, Dong Fang, GengYan Xiong, Xuesong Li*, LiQun Zhou. Validation of the Pretreatment NeutrophiltoLymphocyte Ratio as a Prognostic Factor in a Large Cohort of Chinese Patients with Upper Tract Urothelial Carcinoma. Chin Med J (Engl). 2017, 130(17):2063-2068. (IF 1.596) 38. Yonghao Zhan, Yifan Li, Bao Guan, Zicheng Wang, Ding Peng, Zhicong Chen, Anbang He, Shiming He, Yanqing Gong, Xuesong Li* and Liqun Zhou*. Long non-coding RNA HNF1A-AS1 promotes proliferation and suppresses apoptosis of bladder cancer cells through upregulating Bcl-2. Oncotarget. 2017;8(44):76656-76665. (IF 5.168) 39. Yonghao Zhan#, Yifan Li#, Bao Guan#, Xiaoying Chen, Zhicong Chen, Anbang He, Shiming He, Yanqing Gong, Ding Peng, Yuchen Liu, Zhiming Cai, Xuesong Li* and Liqun Zhou*. Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma. Oncotarget. 2017;8(27):44326-44334. (IF 5.168) 40. Xiaohong Su#, Han Hao#, Xuesong Li*, Zhisong He, Kan Gong, Cuijian Zhang, Lin Cai, Qian Zhang, Lin Yao, Yi Ding, Yanqing Gong, Dong Fang, Zheng Zhang and Liqun Zhou*. Fluorescence in situ hybridization status of voided urine predicts invasive and high-grade upper tract urothelial carcinoma. Oncotarget. 2017;8(16):26106-26111. (IF 5.168) 41. Wenlong Zhong#, Rongcheng Lin#, Lei Zhang, Chengyue Jin, Xuesong Li*, Qun He, Kan Gong, Zhisong He, Liqun Zhou*. Clinicopathologic characteristics, therapy and outcomes of patients with primary ureteral small cell carcinoma: a case series and systematic review of the literature. OncoTargets Ther. 2017; 10:4105-4111. (IF 2.656) 42. Wenlong Zhong#, Lei Zhang#, Jiajian Ma, Shan Shao, Rongcheng Lin, Xuesong Li*, Gengyan Xiong, Dong Fang, Liqun Zhou*. Impact of aristolochic acid exposure on oncologic outcomes of upper tract urothelial carcinoma after radical nephroureterectomy. OncoTargets Ther. 2017; 10:5775-5782. (IF 2.656) 43. Wenlong Zhong, Yicong Du, Lei Zhang, Xuesong Li*, Cuijian Zhang, Dong Fang, Gengyan Xiong, Zhisong He, and Liqun Zhou*. The Application of Internal Suspension Technique in Retroperitoneal Laparoscopic Partial Nephrectomy for Renal Ventral Tumors. BioMed Res Int. 2017;2017(5i):1-7. (IF 2.583) 44. Yunchao Xing#, Gengyan Xiong#, Dong Fang, Xinyu Yang, Xuesong Li*, Liqun Zhou*. Prognostic Value of Gene Methylation and Clinical Factors in Non-Muscle-Invasive Upper Tract Urothelial Carcinoma After Radical Nephroureterectomy. Clin Genitourin Cancer. 2016;14(4): e371-e378. (IF 2.539) 45. Pei Liu, Xiaohong Su, Gengyan Xiong, Xuesong Li*, Liqun Zhou. Diagnostic Ureteroscopy for Upper Tract Urothelial Carcinoma is Independently Associated with Intravesical Recurrence after Radical Nephroureterectomy. Int Braz J Urol. 2016; 42 (6): 1129-1135. (IF 0.976) 46. Xiaohong Su#, Dong Fang#, Lei Zhang, Gengyan Xiong, Han Hao, Guangzhi Zhao, Kunlin Yang, Yunchao Xing, Xuesong Li*, Liqun Zhou*. 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DOI:10.3877/cma.j.issn.1674-0785.2011.03.005. 77. 张崔建,杨新宇,李学松*, 等.肾脏非成熟囊性畸胎瘤一例报道及文献回顾[J].中华临床医师杂志(电子版),2010,04(12):2563-2566. DOI:10.3877/cma.j.issn.1674-0785.2010.12.042. 78. 荣建红,张岩,李学松*, 等.泌尿系子宫内膜异位症的诊断及治疗(附22例报告)[J].北京大学学报(医学版),2010,42(4):461-464. DOI:10.3969/j.issn.1671-167X.2010.04.023. 79. 李学松#,宋毅,龚侃, 等.舒尼替尼治疗转移性肾脏透明细胞癌的临床研究[J].中华外科杂志,2010,48(5):375-377. DOI:10.3760/cma.j.issn.0529-5815.2010.05.015. 80. 李学松#,龚侃,孙国锋, 等.Bcl-2和Bax在前列腺癌不同周期时相的表达[J].中华外科杂志,2008,46(10):768-771. DOI:10.3321/j.issn:0529-5815.2008.10.013. 81. 李日清,李学松*,张祥华, 等.原发性附睾肿瘤——附42例报告[J].中华临床医师杂志(电子版),2007,1(7):14-17. DOI:10.3969/j.issn.1674-0785.2007.07.006. 82. 李学松#,李淑清,何志嵩, 等.射频消融治疗肾肿瘤[J].中华临床医师杂志(电子版),2007,1(7):7-10. DOI:10.3969/j.issn.1674-0785.2007.07.003. 83. 李学松#,李日清,张祥华, 等.腹腔镜在苗勒管持续存在综合征诊断治疗中的应用——病例报告附录像[J].中华临床医师杂志(电子版),2007,1(7):50-51. DOI:10.3969/j.issn.1674-0785.2007.07.017. 84. 李学松#,周利群,何志嵩, 等.聚集素在前列腺癌细胞不同周期时相的表达[J].中华泌尿外科杂志,2006,27(1):36-39. 85. 李学松#,厉将斌,梁云燕, 等.紫龙金联合雌二醇氮芥对小鼠前列腺癌体内抑瘤作用的研究[J].中华泌尿外科杂志,2005,26(12):803-805. 86. 李学松#,肖云翔,周利群, 等.成人前列腺囊高分化鳞癌一例[J].中华外科杂志,2005,43(2):135. 87. 李学松#,白龙伟,陈捷, 等.肾脏平滑肌瘤三例报告[J].中华泌尿外科杂志,2004,25(10):675. 88. 李学松#,梁云燕,王代树, 等.紫龙金对前列腺癌细胞系DU-145的体外作用[J].中华实验外科杂志,2004,21(6):720-722. 89. 李学松#,梁云燕,王代树, 等.复方中药紫龙金对前列腺癌的体外作用[J].中华泌尿外科杂志,2004,25(8):516-520. 90. 李学松#,梁云燕,王代树, 等.复方中药紫龙金对前列腺癌细胞系LNCaP的体外作用[J].中国中西医结合杂志,2004,24(7):621-624. 91. 李学松#,何志嵩*.激素难治性前列腺癌治疗进展[J].中国肿瘤,2003,12(12):699-703. [1]

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李学松 主任医师 北京大学第一医院 泌尿外科
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泌尿系肿瘤的腔镜及开放手术,腹腔镜肾脏部分切除术。腹腔镜肾癌根治术+淋巴结清扫,经腹完全腹腔镜肾输尿管全长切除术,腹腔镜及开放保留神经前列腺癌根治术,膀胱肿瘤电切术,膀胱癌根治术+盆腔淋巴结清扫术+回肠原位新膀胱术,腹腔镜和开放手术治疗输尿管疾病(包括输尿管长段缺损的肠代输尿管术)。晚期肾癌靶向药物治疗。

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"北京大学第一医院泌尿外科主任医师,1999年毕业于北京医科大学临床医学系,获学士学位。同年免试保送研究生,师从北京大学泌尿外科研究所薛兆英教授和郭应禄院士。2004年获北京大学医学部泌尿外科临床医学博士学位,并被评为北京大学优秀毕业生。同年任主治医师,2009晋升为副主任医师,2012年晋升为副教授,2016年晋升为主任医师。2009年-2010年美国旧金山大学医学院(UCSF) 访问学者、2013年3月-5月,美国南加州大学医学院(USC)访问学者。现为中国医师协会泌尿外科医师分会第二届委员兼副总干事,中华医学会泌尿外科学分会青年委员、,北京医学会泌尿外科学分会青年委员会副主任委员、中国医促会泌尿生殖委员会第一届委员,WHO泌尿外科疾病国际共识(SIU-ICUD)咨询委员会成员,中国医师协会全国医师定期考核泌尿外科专业编委会工作秘书、北京市自然科学基金评审专家、强生泌尿外科腹腔镜高级培训班讲师、美国泌尿外科学会(AUA)国际会员、2014及2015年度中国医师百强榜膀胱癌专业上榜专家、2015年度第一届郭应禄泌尿外科青年医师奖获得者。目前担任《泌尿男科时讯》编辑部主任,《Current Opinion in Urology》中文版编辑部主任,《泌尿外科杂志(电子版)》副主编、《现代泌尿外科杂志》、《Translational Andrology and Urology》和《Journal of Tumor》编委,《中华临床医师杂志》和《北京大学学报医学版》特约编委,《Andrology》、《Annals of Surgical Oncology 》《Oncotarget 》、《Urology》、《Canadian Journal of urology》、《Clinical Genitourinary Cancer》、《Chinese medical Journal》及《Urology Annals》等英文杂志以及《中国医学科学院学报》等中文杂志审稿专家。目前专业方向为泌尿系肿瘤以及输尿管和膀胱重建手术。参与科研基金项目6项。其中作为主要申请人承担基础及临床研究基金4项,累计科研经费80余万元。目前作为导师及副导师指导临床研究生20余名,已指导毕业博士研究生5名。 在国内最早较大规模的报道完全经腹腹腔镜肾脏输尿管全长切除手术,并改进输尿管末端袖状切除技术;优化经腹腹腔镜肾癌根治手术的关键步骤;改进腹腔镜膀胱癌根治及回肠原位新膀胱技术;在北大医院泌尿科首次完成肠代输尿管治疗疑难的长段输尿管缺损病例,并进行关键技术改良,后续的二十几例肠代输尿管手术患者临床疗效超过国际报道的水平;改良并标准化经腹腹腔镜肾盂成型缝合技术,降低缝合技术难度,缩短手术时间,提高了手术成功率。与普通外科合作进行腹腔镜全盆腔脏器切除术治疗晚期和复发盆腔肿瘤,减少了手术创伤,缩短了患者术后恢复时间。有多项创新改良手术技术:如成人巨输尿管体外裁剪乳头成型体内再植、经腹腹腔镜肾盂成型手术、改良肠代输尿管手术、输尿管末端袖状切术、腹腔镜肾部分切除内部悬吊技术等手术方法,作为新型手术技术在国际上被认可,发表在《Urology》等国际知名杂志的手术技术栏目上。成人巨输尿管腹腔镜手术和腔内治疗的比较研究被2016年美国AUA年会选为大会发言,马蹄肾成型手术入选2017年AUA视频集锦。 自2009年起,每年在北京大学泌尿外科研究所主办的国际微创技术学习班中表演经腹腹腔镜肾癌根治术、肾输尿管全长切除术,腹腔镜肾盂成型等手术。2015年,受亚洲泌尿年会组委会邀请在亚洲泌尿年会上做腹腔镜肾盂成型手术演示。此外,在过去的7年中,接受全国数十家医学中心邀请,做手术演示、手术会诊及会议讲座。 在医学研究方面,开展了国内最早最大规模对小肾癌体内的自然病程研究,研究目前已经长达13年,发表数篇SCI文章及核心期刊论文,增进了医学界对小肾癌自然病程,手术方式选择,疾病进展及预后的了解,在2015年的国际泌尿年会(SIU)上作为肾肿瘤国际共识撰写专家参与ICUD肾脏肿瘤的撰写和大会汇报;在针对上尿路尿路上皮肿瘤(UTUC)的系列研究中发现了中国人群特有的疾病特征,目前UTUC相关系列研究结果在国际上引起广泛关注,并对临床诊治指南提供了中国的循证医学证据,其中上尿路肿瘤术后膀胱灌注的荟萃分析结果被欧洲(EAU)的UTUC指南引用。在国内最早并系列报道晚期肾癌靶向药物治疗效果及不良反应数据,提出中国患者与西方国家具有一定差异,为国内同道用药提供参考。参与多项国际多中心临床药物试验研究,在多吉美、索坦、阿西替尼等治疗晚期肾癌靶向药物的临床研究中积累了丰富的临床经验。在担任中国肾癌病人援助项目指定医生期间先后诊治全国各地的晚期肾癌患者上百例。"代表性文章 (#第一作者; *通讯作者) SCI文章 1. He A, He S, Huang C, ... Li X* et al. MTDH promotes metastasis of clear cell renal cell carcinoma by activating SND1-mediated ERK signaling and epithelial-mesenchymal transition. Aging (Albany NY). 2020;12(2):1465-1487. (IF 4.831) 2. Zhan Y, Chen Z, He S, ... Li X* et al. Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2. Mol Cancer. 2020;19(1):25. (IF 15.302) 3. Xiong S, Zhu W, Li X, Zhang P, Wang H, Li X*. Intestinal interposition for complex ureteral reconstruction: A comprehensive review. Int J Urol. 2020;27(5):377-386. (IF 2.445) 4. Lu H, Liang Y, Guan B, ... Li X* et al. Aristolochic acid mutational signature defines the low-risk subtype in upper tract urothelial carcinoma. Theranostics. 2020;10(10):4323-4333. (IF 8.579) 5. Wang J, Xiong S, Fan S, ... Li X * et al. Appendiceal Onlay Flap Ureteroplasty for the Treatment of Complex Ureteral Strictures: Initial Experience of Nine Patients. J Endourol. 2020;34(8):874-881. (IF 2.322) 6. Ji G, Huang C, He S, ... Li X* et al. Comprehensive analysis of m6A regulators prognostic value in prostate cancer. Aging (Albany NY). 2020;12(14):14863-14884. (IF 4.831) 7. Xiong S, Wang J, Zhu W, ... Li X * et al. Onlay Repair Technique for the Management of Ureteral Strictures: A Comprehensive Review. Biomed Res Int. 2020; 2020:6178286. (IF 2.276) 8. Fan S, Yin L, Yang K, ... Li X * et al. Posteriorly augmented anastomotic ureteroplasty with lingual mucosal onlay grafts for long proximal ureteral strictures: Ten cases of experience. J Endourol. 2020. (IF 2.322) 9. Cheng S, Fan S, Wang J, ... Li X* et al. Laparoscopic and robotic ureteroplasty using onlay flap or graft for the management of long proximal or middle ureteral strictures: our experience and strategy[J]. International Urology and Nephrology, 2020(7):1-10. (IF 1.843) 10. Bao Guan #, Shiying Tang #, Yonghao Zhan #, Yifan Li, Dong Fang, Ding Peng, Yanqing Gong, Shiming He, Lei Zhang, Kunlin Yang, Gengyan Xiong, Libo Liu, Qun He, Xuesong Li*, Liqun Zhou*. Prognostic performance of the 1973 and 2004 WHO grading classification in upper tract urothelial carcinoma. Urol Oncol. 2019. (IF 3.397) 11. Yifan Li #, Bao Guan #, Jingtao Liu #, Zhongyuan Zhang, Shiming He, Yonghao Zhan, Boxing Su, Haibo Han, Xiaochun Zhang, Boqing Wang, Xuesong Li*, Liqun Zhou*, Wei Zhao*. MicroRNA-200b is downregulated and suppresses metastasis by targeting LAMA4 in renal cell carcinoma. EBioMedicine. 2019. (IF 6.183) 12. Yifan Li#, Shiming He#, Anbang He, Bao Guan, Guangzhe Ge, Yonghao Zhan, Yucai Wu, Yanqing Gong, Ding Peng, Zhengqing Bao, Xuesong Li*, Liqun Zhou*. Identification of plasma secreted phosphoprotein 1 as a novel biomarker for upper tract urothelial carcinomas. Biomed Pharmacother. 2019; 113: 108744. (IF 3.457) 13. Wenlong Zhong#, Peng Hong#, Guangpu Ding#, Kunlin Yang, Xuesong Li*, Junsheng Bao, Guochang Bao,Liang Cui, Changping Men, Zhe Li, Peng Zhang, Ning Chu and Liqun Zhou*. Technical considerations and outcomes for ileal ureter replacement: a retrospective study in China. BMC Surgery, 2019; 19:9. (IF 1.692) 14. Peng Hong#, Ziao Li#, Dongdong Zhu#, Liyan Zhuang, Kunlin Yang, Han Hao, Xuesong Li*, Liqun Zhou*. A Simple Modification for the Usage of Flexible Cystoscope in Modified Laparoscopic Pyeloplasty for Ureteropelvic Junction Obstruction with Renal Calculi: A Flexible Guiding Tube. Urol Int. 2019;102(3):262-268. (IF 1.508) 15. Yifan Li#, Dong Fang#, Zhengqing Bao#, Anbang He, Bao Guan, Shiming He, Yonghao Zhan, Yanqing Gong, Xuesong Li*, Liqun Zhou*. High aspartate transaminase/alanine transaminase ratio predicts poor prognosis in patients with localized upper tract urothelial cancer: a propensity score-matched study in a large Chinese center. OncoTargets Ther, 2019;12:2635-2648. (IF 2.656) 16. Peng Hong, Yukun Cai, Ziao Li, Shubo Fan, Kunlin Yang, Han Hao, Qun He, Xuesong Li*, Liqun Zhou*. Modified Laparoscopic Partial Ureterectomy for Adult Ureteral Fibroepithelial Polyp: Technique and Initial Experience. Urol Int. 2018;102(1):13-19. (IF 1.508) 17. Zhuo Jia#, Yanqing Gong#, Cuijian Zhang, Zhengqing Bao, Xuesong Li*, Han Hao, Gengyan Xiong, Lei Zhang, Dong Fang, Zhisong He, Liqun Zhou*. Segmental ureterectomy can be performed safely in patients with urothelial carcinoma of distal ureter. Can Urol Assoc J. 2018;13(7). (IF 1.179) 18. Yifan Li#, Yanqing Gong#, Xianghui Ning, Ding Peng, Libo Liu, Shiming He, Kan Gong, Cuijian Zhang*, Xuesong Li* and Liqun Zhou*. Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis. J Exp Clin Cancer Res. 2018;37(1):276. (IF 6.217) 19. Yonghao Zhan, Zhicong Chen, Yifan Li, Anbang He, Shiming He, Yanqing Gong, Xuesong Li* and Liqun Zhou*. Long non-coding RNA DANCR promotes malignant phenotypes of bladder cancer cells by modulating the miR-149/MSI2 axis as a ceRNA. J Exp Clin Cancer Res. 2018;37(1):273. (IF 6.217) 20. Anbang He#, Shiming He#, Xuesong Li*, Liqun Zhou*. ZFAS1: A novel vital oncogenic lncRNA in multiple human cancers. Cell Proliferation. 2018;66(4): e12513. (IF 4.936) 21. Ding Peng, Guangzhe Ge, Zhengzheng Xu, Qin Ma, Yue Shi, Yuanyuan Zhou, Yanqing Gong, Gengyan Xiong, Cuijian Zhang, Shiming He, Zhisong He, Xuesong Li*, Weimin Ci* and Liqun Zhou*. Diagnostic and prognostic biomarkers of common urological cancers based on aberrant DNA methylation. Epigenomics. 2018;10(9):1189-1199. (IF 4.979) 22. Zhicong Chen#, Yonghao Zhan#, Jieshan Chi#, Shuyuan Guo#, Xinliang Zhong, Anbang He, Jianrong Zheng, Yanqing Gong, Xuesong Li*, Liqun Zhou*. Using microRNAs as Novel Predictors of Urologic Cancer Survival: An Integrated Analysis. EBioMedicine. 2018; 34:94-107. (IF 6.183) 23. Guangzhe Ge#, Ding Peng#, Ziying Xu#, Bao Guan, Zijuan Xin, Qun He, Yuanyuan Zhou, Xuesong Li*, Liqun Zhou* and Weimin Ci*. Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth. EMBO Reports. 2018;19(8): e45401. (IF 8.749) 24. Ding Peng, Guangzhe Ge, Yanqing Gong, Yonghao Zhan, Shiming He, Bao Guan, Yifan Li, Ziying Xu, Han Hao, Zhisong He Gengyan Xiong, Cuijian Zhang, Yue Shi, Yuanyuan Zhou, Weimin Ci*, Xuesong Li* and Liqun Zhou*. Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer. Clin Epigenetics. 2018;10(1):94. (IF 6.091) 25. Bao Guan#, Yunchao Xing#, Gengyan Xiong#, Zhenpeng Cao, Dong Fang, Yifan Li, Yonghao Zhan, Ding Peng, Libo Liu, Xuesong Li* and Liqun Zhou*. Predictive value of gene methylation for second recurrence following surgical treatment of first bladder recurrence of a primary upper-tract urothelial carcinoma. Oncology Letters. 2018;15(6):9397-9405. (IF 1.664) 26. Ding Peng#, Cuijian Zhang#, Yanqing Gong*, Han Hao, Bao Guan, Xuesong Li* and Liqun Zhou*. Prognostic significance of HALP (hemoglobin, albumin, lymphocyte and platelet) in patients with bladder cancer after radical cystectomy. Scientific Reports. 2018; 8:794. (IF 4.122) 27. Ding Peng#, Cui-jian Zhang#, Qi Tang, Lei Zhang, Kai-wei Yang, Xiao-teng Yu, Yanqing Gong, Xue-song Li*, Zhi-song He and Li-qun Zhou*. Prognostic significance of the combination of preoperative hemoglobin and albumin levels and lymphocyte and platelet counts (HALP) in patients with renal cell carcinoma after nephrectomy. BMC Urol, 2018, 18:20. (IF 1.792) 28. Dong Fang#, Shiming He#, Gengyan Xiong#, Nirmish Singla, Zhenpeng Cao, Lei Zhang, Xuesong Li* and Liqun Zhou*. Comparison of clinicopathologic characteristics, epigenetic biomarkers and prognosis between renal pelvic and ureteral tumors in upper tract urothelial carcinoma. BMC Urol. 2018;18(1):22. (IF 1.792) 29. Bao Guan#, Yicong Du#, Xiaohong Su#, Zhenpeng Cao, Yifan Li, Yonghao Zhan, Ding Peng, Gengyan Xiong, Dong Fang, Yi Ding, Shiming He, Yanqing Gong, Qun He, Xuesong Li* and Liqun Zhou*. Positive urinary fluorescence in situ hybridization indicates poor prognosis in patients with upper tract urothelial carcinoma. Oncotarget. 2018;9(18):14652-14660. 30. Run-Qi Guo#, Geng-Yan Xiong#, Kai-Wei Yang, Lei Zhang, Shi-Ming He, Yan-Qing Gong, , Qun He, Xue-Ying Li, Zi-Cheng Wang, Zhen-Qing Bao, Xue-Song Li*, Kai Zhang, Li-Qun Zhou*. Detection of urothelial carcinoma, upper tract urothelial carcinoma, bladder carcinoma, and urothelial carcinoma with gross hematuria using selected urine-DNA methylation biomarkers: A prospective, single-center study. Urol Oncol. 2018; 36(7): 342.e15-342.e23. (IF 3.397) 31. Shiying Tang, Han Hao, Dong Fang, Wei Zheng, Peng Ge, Xiaohong Su, Qun He, Xinyu Yang , Qi Shen, Xuesong Li*, Wei Yu, Jian Lin, Liqun Zhou. Prostate cancer incidentally discovered at the time of radical cystoprostatectomy does not decrease overall survival: Results from a large Chinese medical center. Int Braz J Urol. 2018;44(2):258-266. (IF 0.976) 32. Peng Hong, Guangpu Ding, Dongdong Zhu, Kunlin Yang, Jinhong Pan*, Xuesong Li*, Zhipeng Chen, Lei Zhang, Qi Tang, Han Hao, Zhansong Zhou and Liqun Zhou. Head-to-Head Comparison of Modified Laparoscopic Pyeloplasty and Robot-Assisted Pyeloplasty for Ureteropelvic Junction Obstruction in China. Urol Int. 2018; 101(3):337-344. (IF 1.508) 33. Gengyan Xiong#, Lin Yao#, Peng Hong#, Li Yang, Weimin Ci, Libo Liu, Qun He, Kan Gong, Xuesong Li* and Liqun Zhou*. Aristolochic acid containing herbs induce gender-related oncological differences in upper tract urothelial carcinoma patients. Cancer Manag Res. 2018;10: 6627-6639. (IF 3.702) 34. Wenlong Zhong#, Lin Yao#, Haoran Cui, Kunlin Yang, Gang Wang, Tao Xu, Xiongjun Ye, Xuesong Li*, Liqun Zhou*. Laparoscopic ureteral reimplantation with extracorporeal tailoring and direct nipple ureteroneocystostomy for adult obstructive megaureter: long-term outcomes and comparison to open procedure. Int Urol Nephrol. 2017;49(11):1973-1978. (IF 1.692) 35. Shiying Tang#, Guochen Niu#, Dong Fang, Ziguang Yan, Bihui Zhang, Xuesong Li*, Min Yang*, Liqun Zhou*. The diagnosis and endovascular therapy of renal artery aneurysm: A 32-patient case report. Medicine (Baltimore). 2017;96(47): e8615. (IF 2.028) 36. Wenlong Zhong#, Yicong Du#, Kunlin Yang, Steven Meng, Rongcheng Lin, Xuesong Li*, Liyan Zhuang, Lin Cai, Haoran Cui, Zhisong He, and Liqun Zhou. Ileal Ureter Replacement Combined with Boari Flap-Psoas Hitch to Treat Full-Length Ureteral Defects: Technique and Initial Experience. Urology. 2017;108: 201-206. (IF 2.3) 37. ZhenPeng Cao, Bao Guan, GuangZhi Zhao, Dong Fang, GengYan Xiong, Xuesong Li*, LiQun Zhou. Validation of the Pretreatment NeutrophiltoLymphocyte Ratio as a Prognostic Factor in a Large Cohort of Chinese Patients with Upper Tract Urothelial Carcinoma. Chin Med J (Engl). 2017, 130(17):2063-2068. (IF 1.596) 38. Yonghao Zhan, Yifan Li, Bao Guan, Zicheng Wang, Ding Peng, Zhicong Chen, Anbang He, Shiming He, Yanqing Gong, Xuesong Li* and Liqun Zhou*. Long non-coding RNA HNF1A-AS1 promotes proliferation and suppresses apoptosis of bladder cancer cells through upregulating Bcl-2. Oncotarget. 2017;8(44):76656-76665. (IF 5.168) 39. Yonghao Zhan#, Yifan Li#, Bao Guan#, Xiaoying Chen, Zhicong Chen, Anbang He, Shiming He, Yanqing Gong, Ding Peng, Yuchen Liu, Zhiming Cai, Xuesong Li* and Liqun Zhou*. Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma. Oncotarget. 2017;8(27):44326-44334. (IF 5.168) 40. Xiaohong Su#, Han Hao#, Xuesong Li*, Zhisong He, Kan Gong, Cuijian Zhang, Lin Cai, Qian Zhang, Lin Yao, Yi Ding, Yanqing Gong, Dong Fang, Zheng Zhang and Liqun Zhou*. Fluorescence in situ hybridization status of voided urine predicts invasive and high-grade upper tract urothelial carcinoma. Oncotarget. 2017;8(16):26106-26111. (IF 5.168) 41. Wenlong Zhong#, Rongcheng Lin#, Lei Zhang, Chengyue Jin, Xuesong Li*, Qun He, Kan Gong, Zhisong He, Liqun Zhou*. Clinicopathologic characteristics, therapy and outcomes of patients with primary ureteral small cell carcinoma: a case series and systematic review of the literature. OncoTargets Ther. 2017; 10:4105-4111. (IF 2.656) 42. Wenlong Zhong#, Lei Zhang#, Jiajian Ma, Shan Shao, Rongcheng Lin, Xuesong Li*, Gengyan Xiong, Dong Fang, Liqun Zhou*. Impact of aristolochic acid exposure on oncologic outcomes of upper tract urothelial carcinoma after radical nephroureterectomy. OncoTargets Ther. 2017; 10:5775-5782. (IF 2.656) 43. Wenlong Zhong, Yicong Du, Lei Zhang, Xuesong Li*, Cuijian Zhang, Dong Fang, Gengyan Xiong, Zhisong He, and Liqun Zhou*. The Application of Internal Suspension Technique in Retroperitoneal Laparoscopic Partial Nephrectomy for Renal Ventral Tumors. BioMed Res Int. 2017;2017(5i):1-7. (IF 2.583) 44. Yunchao Xing#, Gengyan Xiong#, Dong Fang, Xinyu Yang, Xuesong Li*, Liqun Zhou*. Prognostic Value of Gene Methylation and Clinical Factors in Non-Muscle-Invasive Upper Tract Urothelial Carcinoma After Radical Nephroureterectomy. Clin Genitourin Cancer. 2016;14(4): e371-e378. (IF 2.539) 45. Pei Liu, Xiaohong Su, Gengyan Xiong, Xuesong Li*, Liqun Zhou. Diagnostic Ureteroscopy for Upper Tract Urothelial Carcinoma is Independently Associated with Intravesical Recurrence after Radical Nephroureterectomy. Int Braz J Urol. 2016; 42 (6): 1129-1135. (IF 0.976) 46. Xiaohong Su#, Dong Fang#, Lei Zhang, Gengyan Xiong, Han Hao, Guangzhi Zhao, Kunlin Yang, Yunchao Xing, Xuesong Li*, Liqun Zhou*. Treatment strategies for upper tract urothelial carcinoma (UTUC) of a solitary kidney: a single-institutional analysis of 61 cases. Int Urol Nephrol. 2016;48(10):1601-1608. (IF 1.692) 47. Lei Zhang, Dong Fang, Xuesong Li*, Lin Yao, Gengyan Xiong, Zhisong He, and Liqun Zhou*. Transperitoneal Subcostal Access for Urologic Laparoscopy: Experience of a Large Chinese Center. BioMed Res Int. 2016;2016(1):1-5. (IF 2.583) 48. Xiaohong Su, Dong Fang, Xuesong Li*, Gengyan Xiong, Lei Zhang, Han Hao, Yanqing Gong, Zheng Zhang, and Liqun Zhou*. The Influence of Tumor Size on Oncologic Outcomes for Patients with Upper Tract Urothelial Carcinoma after Radical Nephroureterectomy. BioMed Res Int. 2016; 2016:1-7. (IF 2.583). 49. Lei Zhang, Lin Yao, Xuesong Li*, Michael A.S. Jewett, Zhisong He, Liqun Zhou*. Natural history of renal cell carcinoma: An immunohistochemical analysis of growth rate in patients with delayed treatment. J Formos Med Assoc. 2015;115(6):463-469. (IF 2.452) 50. Qi Tang#, Gengyan Xiong#, Xuesong Li*, Dong Fang, Chenguang Xi, Lei Zhang, Kaiwei Yang, Lin Yao, Cuijian Zhang, Wei Yu, Qun He, Kan Gong, Zhisong He, Liqun Zhou*. The prognostic impact of squamous and glandular differentiation for upper tract urothelial carcinoma patients after radical nephroureterectomy. World J Urol. 2015;34(6):871-877. (IF 2.981) 51. Pei Liu#, Dong Fang#, Gengyan Xiong, Kaiwei Yang, Lei Zhang, Lin Yao, Cuijian Zhang, Xuesong Li*, Zhisong He, Liqun Zhou*. A Novel and Simple Modification for Management of Distal Ureter During Laparoscopic Nephroureterectomy Without Patient Repositioning: A Bulldog Clamp Technique and Description of Modified Port Placement. J Endourol. 2015;30(2):195-200. (IF 2.038) 52. Dong Fang#, Pei Liu#, Xuesong Li*, Gengyan Xiong, Lei Zhang, Nirmish Singla, Guangzhi Zhao, Qun He, Zhisong He and Liqun Zhou*. Characteristics and treatment outcomes of pan-urothelial cell carcinoma: a descriptive analysis of 45 patients. 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Xiaoteng Yu#, Gang Guo#, Xuesong Li#, Cuijian Zhang, Lihua Huang, Dong Fang, Yi Song, Xu Zhang, and Liqun Zhou*. Retrospective Analysis of the Efficacy and Safety of Sorafenib in Chinese Patients with Metastatic Renal Cell Carcinoma and Prognostic Factors Related to Overall Survival. Medicine (Baltimore). 2015;94(34): e1361. (IF 2.028) 57. Lei Zhang, Xuesong Li*, Liqun Zhou*. Natural History of Small Renal Masses. Chin Med J (Engl). 2015; 128(9): 1232–1237. (IF 1.596) 58. Gengyan Xiong#, Jin Liu#, Qi Tang, Yu Fan, Dong Fang, Kaiwei Yang1, Feng Xie, Min Zhang, Lei Zhang, Libo Liu, Cuijian Zhang, Lin Yao, Li Yang, Weimin Ci, Wei Zhao, Yanqing Gong, Qun He, Kan Gong, Zhisong He, Gang Wang, Xuesong Li*, Yinglu Guo and Liqun Zhou#. Prognostic and predictive value of epigenetic biomarkers and clinical factors in upper tract urothelial carcinoma. Epigenomics. 2015;7(5):733-744. (IF 4.979) 59. Dong Fang#, Lei Zhang#, Xuesong Li*, Wei Yu, Nirmish Singla, Guangzhi Zhao, Gengyan Xiong, Yi Song, Qun He, Zhisong He, and Liqun Zhou*. Presence of Concomitant Non-muscle-invasive Bladder Cancer in Chinese Patients with Upper Tract Urothelial Carcinoma: Risk Factors, Characteristics, and Predictive Value. Ann Surg Oncol. 2015;22(8):2789-2798. (IF 3.857) 60. Bentao Shi#, Boxing Su#, Dong Fang, Yuan Tang, Gengyan Xiong, Zhongqiang Guo, Qun He, Xinyu Yang, Wei Zhao, Yinglu Guo, Xuesong Li* and Liqun Zhou*. High expression of KPNA2 defines poor prognosis in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy. BMC Cancer. 2015;15(1):380. (IF 3.288) 61. Dong Fang#, Gengyan Xiong#, Xuesong Li*, Yongming Kang, Lei Zhang, Guangzhi Zhao, Xiaopeng Chen, Lin Yao, Xiaoyu Zhang, Wei Yu, Kan Gong, Yi Song, Qun He, Zhisong He, Liqun Zhou*, Yinglu Guo. 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